Australia regained the Women's Ashes after England collapsed to 87 all out to lose the second Twenty20 international by 20 runs.
Needing to win at Hove to keep the multi-format series alive, England were chasing 108 but slipped to 10-3 and 23-5, with Ellyse Perry taking 2-13.
Lydia Greenway made 26, but was last out with five balls to go.
Australia, who managed only 107-7, take an unassailable 10-4 lead on points with just one T20 remaining.


In doing so, the Southern Stars win the Ashes for the first time since 2010-11, England having won on both occasions since the multi-format of three one-day internationals, a Test and three T20s was introduced in 2013.
Behind 8-4 after losing the Test and two of the ODIs, a superb bowling display meant the hosts required only a modest target to take the series into a deciding T20 in Cardiff on Monday.
But, as with most of the series, England's batting was once again below par and they crumbled to their lowest ever T20 score.